Transplantation of Melanomas from Platyfish-Swordtail Hybrids into Embryos of Swordtails, Platyfish and their Hybrids
نویسندگان
چکیده
منابع مشابه
Animal model for ultraviolet radiation-induced melanoma: platyfish-swordtail hybrid.
Sunlight exposure is strongly indicated as one of the important etiologic agents in human cutaneous malignant melanoma. However, because of the absence of good animal models, it has not been possible to estimate the wavelengths or wavelength regions involved. We have developed a useful animal model from crosses and backcrosses of platyfish (Xiphophorus maculatus) and swordtails (Xiphophorus hel...
متن کاملA CDKN2-like polymorphism in Xiphophorus LG V is associated with UV-B-induced melanoma formation in platyfish-swordtail hybrids.
The genetic basis of spontaneous melanoma formation in spotted dorsal (Sd) Xiphophorus platyfish-swordtail hybrids has been studied for decades, and is adequately explained by a two-gene inheritance model involving a sex-linked oncogene, Xmrk, and an autosomal tumor suppressor, DIFF. The Xmrk oncogene encodes a receptor tyrosine kinase related to EGFR; the nature of the DIFF tumor suppressor ge...
متن کاملGenetics of Melanomas in Fishes V. The Reappearance of Ancestral Micromelanophores in Offspring of Parents Lacking These Cells*
In previous papers in this series (5, 8, I3) it has been shown that spontaneous malignant melanomas are produced in the hybrid offspring of the black-spotted platyfish, Platypoecilus maculatus, and the swordtail, Xiphophorus hdlerii. The melanomas are evoked genetically in hybrids by the interaction of the sexlinked, heritable factor for macromelanophores, Sp, of the platyfish with a series of ...
متن کاملEstablishment of a cell line from the platyfish-swordtail hybrid melanoma.
A fish melanoma cell line, PSM-1, was established from a hereditary melanoma in an interspecific hybrid of Xiphophorus for cytogenetic studies of this melanoma system. An amelanotic melanoma was obtained from the tail fin of a melanotic F1 hybrid between a spotted platyfish (Xiphophorus maculatus) and an albino swordtail (Xiphophorus helleri). The tumor tissue was dissociated and cultured in Ea...
متن کاملStudy and identification of external parasites in platyfish imported into Iran
Ornamental fish keeping is developing in Iran. Most of these fishes are not native and importing. External parasite is one of the most important difficulties in aquarium fishes. The aim of this study is determination of parasite pollution in skin and gills of imported platy fish. One hundred and fifty out of 220 platy fish was polluted. Parasites identification was done by wet mount, Stainin...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Biology
سال: 1957
ISSN: 1477-9145,0022-0949
DOI: 10.1242/jeb.34.4.518